In the US, one in three people will develop cancer. There is a good probability that you or a loved one has battled cancer. The following information can help you better understand cancer. Throughout your lifespan, your billions of cells will typically grow and divide as needed. Most cells die when they become unusual or aged. When something goes wrong during this process, your cells continue to divide, preventing the old or abnormal cells from dying as they should.

Lung Cancer: Cancer is a condition in which the body's cells proliferate unchecked. The term "lung cancer" refers to cancer that develops first in the lungs. Lung cancer can begin in the lungs in addition to lymph nodes and other body parts like the brain. There is a chance that lung cancer will spread to other organs. Cancer cells that have moved from one organ to another are known as metastases. Small cell and non-small cell lung tumors are the two primary subtypes that are typically recognized (including adenocarcinoma and squamous cell carcinoma). These numerous types of lung cancer have distinctive patterns of development and therapeutic responses. The incidence of non-small cell lung cancer is higher than that of small cell lung cancer.

Risk factor of Lung cancer

Smoking: The leading cause of lung cancer risk is cigarette smoking. About 80% to 90% of lung cancer deaths in the US are attributed to smoking cigarettes. Lung cancer risk is increased by using tobacco products, including cigars, pipes, and other cigarettes. Tobacco smoke is a dangerous cocktail of almost 7,000 chemicals. Many are toxic. At least 70 have been connected to either human or animal cancer. Smokers have a 15-30 times higher chance of acquiring lung cancer or dying from it than nonsmokers.

Smokers who give up have a lower chance of lung cancer than if they hadn't quit, but their risk is still higher than that of non-smokers. Smoking cessation can reduce lung cancer risk at any age. Smoking increases the risk of cancer in almost every area of the body. Smoking cigarettes increases the risk of developing acute myeloid leukemia and cancers of the mouth, throat, esophagus, stomach, colon, rectum, liver, pancreas, voice box (larynx), trachea, and bronchi.

Radon: In the US, radon is second only to smoking as a cause of lung cancer. Natural gas called radon can originate in water, soil, and rocks. It is odorless, tasteless, and transparent. When radon enters homes or structures through cracks or holes, it may become trapped and begin to accumulate in the air. High radon levels are inhaled by those who reside or work in these homes and buildings. Radon exposure over a lengthy period of time can result in lung cancer.

Other Substances: Asbestos, arsenic, diesel exhaust, and certain kinds of silica and chromium are a few examples of pollutants that can be found in some industries and enhance risk. Smokers are at a significantly increased risk of developing lung cancer from many of these drugs.

If your parents, siblings, children, or other family members have had lung cancer, your risk may be increased. This may be the case because they smoke as well or because they share a home or workplace where radon and other carcinogens that can lead to lung cancer are present.

Types of lung Cancer

Non-small cell lung cancer: NSCLC accounts for about 80–85% of lung cancer cases. The three main kinds of NSCLC are adenocarcinoma, squamous cell carcinoma, and giant cell carcinoma. These kinds of NSCLC, which originate from many types of lung cells, are included because of how similarly they are often treated and prognoses.

1. Adenocarcinoma: Cells that ordinarily release things like mucus are where adenocarcinomas develop. This type of lung cancer primarily affects those who currently smoke or have smoked in the past, despite the fact that it is also the most common type to be seen in non-smokers. Compared to other forms of lung cancer, it is more prevalent in women than in men and is more likely to affect younger people.
2. Squamous carcinoma: Which are flat cells that line the lining of the lungs' airways, are where squamous cell carcinomas originate? They frequently occur in the center of the lungs, close to a major airway, and are frequently associated with a history of smoking (bronchus).
3. Undifferentiated large cell carcinoma: Any area of the lung can develop large cell carcinoma. It frequently multiplies and spreads, which might make treatment more challenging. Big cell neuroendocrine carcinoma, a subtype of large cell carcinoma, is a swiftly progressing malignancy that resembles small cell lung cancer greatly.

Small cell lung cancer:  SCLC, also known as oat cell carcinoma, accounts for 10% to 15% of all cases of lung cancer. This form of lung cancer tends to advance and spread more rapidly than NSCLC. When diagnosed with SCLC, almost 70% of patients already had the disease disseminated throughout their bodies. Due to how quickly it spreads, this cancer usually responds well to chemotherapy and radiation treatments. Unfortunately, the cancer will eventually come back for the majority of people.

Clinical Oncology Case Reports

Clinical Oncology Case Reports is a peer-reviewed, multidisciplinary worldwide publication devoted to cancer research. It is an interdisciplinary publication with a high impact that focuses on clinical and medical research. Due to its multidisciplinary approach, readers are brought up to date on recent developments in both related and their own fields of study. The Journal focuses on all forms of malignant disease and treatment, including systemic therapy, radiation, pathology, diagnostics, and therapy.

Journal Highlights

• Anti-Cancer Drug
• All type of Cancer
• Cancer Epidemiology
• Cancer gene therapy
• Carcinogenesis
• Chemotherapy
• Tumor Immunity
• Immune check point inhibitor
• Endometrial cancer
• Carcinosarcoma
• Hormone Therapy
• Stem cell transplants, etc.
   

Submission Link: https://www.scholarscentral.org/submissions/clinical-oncology-case-reports.html

Domain: oncologyreport@escienceopen.com